What are you going to pull behind it?
The major issues for using them commercially (I've thought about it myself!) are:
5th wheel height - it's too tall to haul most trailers without the trailer ending up being on a stupid angle, and van trailers will be overheight. It's /way/ higher than a civilian 5th wheel. I don't know the height off hand but it's at least a foot higher than the 48" standard for commercial.
The 5th wheel is full oscillating which is awesome for off road, but it's only rated at 25,000LB for some reason despite looking as heavy as 100,000LB ones I've seen commercially. This might be an issue with the DOT but might not. Doesn't matter if you aren't pulling heavy trailers though. And might not really matter if you are. The rating is clearly ignored by the military, since there's pictures of them hauling trailers that empty weigh 25K and have two 30+Klb APC's on the trailer.
MPG... It's ****. You'll probably get 6-7 if you are lucky and hauling light stuff. You might get 3 if you are hauling heavy in town. Compare to a modern semi at 6 worst case and 12 best case.
full time AWD means maintenance might eat you alive.
60 MPH is screaming it.. Not a huge deal if the temps stay reasonable aside from the whole MPG thing.
With all that said, none of these issues are insurmountable and may not be deal breakers for you. But they're definitely issues that require consideration.
