It's not a matter of whether they're SPRAG (that's how you spell it) transfer cases or full-time 6 wheel drive.
Trucks either had the Sprag or they were upgraded to air-shift transfer cases. Either way, none have their front axles engaged full time.
Air-shift, you flip a switch and it uses compressed air and a piston to engage the driveline to the front axle.
Sprag, the design of the gear-system inside the transfer case senses when the rear axles slip (spinning but without resistance) and engages the driveline to the front axle.
EDIT: When the Sprag transfer case is adjusted properly, it works beautifully. The Air-shift trucks are more desirable to some because they are easier to work on and simpler. Either way, the trucks should be fine to drive on the highway, as long as the front axle isn't engaged. Unless the Sprag trucks have damaged transfer cases (unlikely), they should be just as fine as the truck with the air-shift case. The 45 MPH stencil is primarily because they didn't want drivers going too fast (60 MPH) and blowing engines, etc... I think 45MPH is also the standard convoy speed.