I've driven that route (the other way...down from Alaska)...let me tell you this: The vehicle should be in tip-top shape, carry extra fuel and several extra tires. Carry enough food and clothing to spend at least one night broken down. Also, check in at the local RCMP stations, tell them where you are going and when you expect to get to the next station...that way if you go missing they know.
Also, fuel is more expensive in Canada, so be prepared for that.
You are *really* out there in the wilderness on the al-can hwy once you get up past central B.C. Little mobile phone reception past there, and almost none once you get into the Yukon territories. Plus you are basically crisscrossing the continental divide for a good part of that trip.
I learned these lessons first hand...be prepared.
BTW: It was one of the most beautiful drives I've ever done....also some of the scariest moments. Imagine pushing snow with your front bumper on the highway...and there's *no* other tracks on the road in either direction, with another 100 miles to go before the next fuel stop (that you hope is still open for the season).
Oh, and Canadians are some of the nicest people you will ever meet. Saved my butt at least twice. Wonderful country, wonderful people. Prepare for an adventure.