I ran close to 100% bio for about 6 years and a 6.9IDI international motor and in tens of thousands of miles I had no real trouble.
In the early days I had to replace a couple fuel filters, which I was warned would happen as the bio dissolved the old sludge in the tanks.
The motor needed fuel return hoses and o-rings at some point, but that's hardly uncommon for those engines so I'd consider it normal maintenance.
I know it's not a good idea to let bio sit around, but life happens and even after a couple years sitting the truck started up and ran fine.
The BD I ran varied, in the early days it was from a couple guys who were enthusiasts but still a pretty backyard operation, later I bought commercial fuel as it became available.
I'd still be running 100%, but the political tides have shifted (don't use food for fuel) so it's gotten harder to come by.
Lately I'm running 20% in the 6.9 as well as a couple New Holland I-6 motors in Ford MDTs.