I was going to write a new thread about this but I figure this would be a great place, I've been running the super singles on the M35a2 for a bit and here's the difference for me (Pros and cons)
Better cruise speed 55-58Mph at 2200-2300 Rpm, much safer than the 45-48Mph on a 70Mph freeway that I use to do
Slower acceleration big time, this is one of the things I miss the most about the smaller 9R20, after I turned the fuel up a little, the truck seemed very sporty and zippy while still staying around 900 Degrees on the EGT gauge, with the 395s, the truck is very slow on acceleration in comparison (Take note, what's zippy and fast to me is most likely slow to you, I daily a humvee)
Grip, the 395s are far better off the payment and in wet weather, I never had any issues with the NDTs on wet pavement because I'm cautious with them in wet weather, in the mud and off pavement, it's not even a comparison, the 395s are a lot better.
Climbing inclines, thankfully I'm in flat Louisiana, but I do go over the I-10 and 210 bridge which is a little bit of a steep incline, the NDTs goes over the bridge with no problem whatsoever and still maintain 45-48 while staying at 900 on the EGT gauge, I cruise with the super singles at 55-58 and it will drop down 45-48 while climbing, the EGTs will be around 1,100-1,200 at that speed. I typically don't like passing 1,000 on the EGT gauge that much.
Turn radius, this depends a lot on what wheels you're running, I'm running the MRAP wheels with the 10.9In backspacing and my right turn is cut short by a lot due to the tire rubbing the steering box, I have the waterloo power steering kit installed, unfortunately you'll get this with almost any power steering box that has to go outside the frame. This can simply be avoided by going with a wheel with a better offset, but your tire will stick out the fender a little, and of course these bigger tires will put more stress on your wheel bearings, transmission, steering, and suspension components etc.
I get about 2MPG more on the 395s in the city, highway is the same but with both of the tires I only cruise at 2200 RPMs mostly
Braking, the brakes are not as bad as I thought they'll be with the 395s but its obviously a lot better with the NDTs, the one thing I did notice is if you have to hard brake, the NDTs will slide in a weird a way, whereas the 395s wouldn't, they'll just stop straight, while the NDTs kind of get this pull to one side slide.
Carrying weight, I really can't speak that much on this since the weight I carry is usually around 2,000-3,000Ibs which is not even noticeable while driving the m35, I would say this, the smaller tires does give you a lower height which makes loading and unloading easier.
Emergency, this is one of those things I'm just throwing out, if you get a blowout while being 100 miles from home, you're basically screwed with the 395s unless you carry a spare in the bed. Also, you'll be on one hell of a ride if you blow one of those steer tires.
Ride Quality, the 395s are a lot smoother and quiet, I notice with the NDTs any crack in the road or pothole would try to jerk the steering wheel a bit, while the 395s just run over them small cracks and potholes like nothing. I will add that the smaller tires are easy to get balanced in comparison to the 395s, surprisingly the previous owner had the wheel and tire balanced where truck would shake at any speed, with the 395s I do get a little bit of shake at 50-58 sometimes but the antifreeze in the tire trick does pretty good.
In my personal opinion, I'm kind of mixed on what tire I prefer, I feel like the truck was a lot more fun to drive around with the small NDTs because of the acceleration and the right turn radius, also having a spare that I can easily pick up and change was nice too. I would also say I feel like I wasn't stressing the steering, multifuel, and spicer out that much with them. The 395s feels like it's just too much for the multifuel. Now the grip, cruise speed, and ride quality are almost unbeatable with the 395s. I would say this though, if I had a better overdrive transmission that let me do 55-60 Mph at 2,000-2,200 RPMs, I would most likely look for a better tire and wheel that's similar to the 9R20 in size or go with the 11R20s